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    Karisma (Rh Collagen) Bangkok | VERZO CLINIC Ekkamai

    Karisma is a premium Korean recombinant human collagen (Rh-Collagen) skinbooster — bioengineered Type-I collagen identical to human skin collagen, with no animal- or porcine-derived material. Unlike polycaprolactone (PCL) biostimulators, Karisma directly replenishes the collagen scaffold of the dermis while triggering native fibroblast collagen synthesis for visible firming, hydration, and luminosity at 4 weeks.

    Karisma Key Facts — 2026

    • Recombinant Human Type-I Collagen — bioengineered identical to human skin collagen
    • Manufacturer: GeneCell International (South Korea)
    • NOT polycaprolactone or PLLA — Karisma is direct collagen replenishment, not synthetic biostimulator
    • Zero animal-derived material — halal/vegan-friendly
    • Registered with the Thai FDA (อย.) for use in Thailand
    • Visible result at 4 weeks; peak at 8–12 weeks
    • Recommended protocol: 3 sessions, 2–3 weeks apart
    • Effect duration: 9–12 months with annual maintenance
    • Often considered for: collagen replenishment after age 25, post-laser recovery, halal patients

    About Karisma (Rh Collagen)

    Manufacturer: GeneCell International (South Korea). Certifications: Registered with the Thai FDA (อย.), Halal-friendly (zero animal-derived material).

    How it works: Karisma is injected superficially into the dermis (0.5–1 mm depth) using nappage or micro-bolus technique. The recombinant collagen integrates immediately into the existing collagen matrix, while signalling fibroblasts to upregulate native COL1A1/COL3A1 expression. Unlike HA fillers (volume) or PLLA/PCL (slow biostimulation), Karisma bridges both — instant collagen replenishment plus 3-month progressive collagen renewal.

    Key technology: Recombinant Human Type-I Collagen produced via E. coli expression — identical amino-acid sequence to native human collagen, zero porcine/bovine antigenicity, halal-friendly

    Treatment Areas

    • Full face (primary indication for skin quality)
    • Neck
    • Décolletage
    • Hands
    • Acne scars

    Who Is Karisma Ideal For?

    • Adults 25+ wanting collagen replenishment without volume change
    • Patients with Rh-Collagen preference (vegan/halal/animal-free)
    • Skin showing fine lines, dullness, or loss of bounce
    • Pre-event skin prep (wedding, photoshoot)
    • Patients who have used HA boosters and want to escalate
    • Post-laser / post-microneedling recovery boost

    Aftercare for Karisma

    • Avoid makeup for 12 hours
    • No intense exercise or sauna for 24 hours
    • Mild redness or pinpoint marks for 1–3 days is normal
    • Gentle cleansing only — avoid retinoids and exfoliants for 48 hours
    • Individual results with 3-session protocol spaced 2–3 weeks apart

    Frequently Asked Questions — Karisma Bangkok 2026

    What is the difference between Karisma and Profhilo?

    Profhilo uses ultra-pure hyaluronic acid (HA) for hydration and bio-remodelling. Karisma uses recombinant human Type-I collagen — it directly replaces the dermal collagen lost with age, not just water-binding HA. For patients who already use HA boosters and want to escalate, Karisma is the next-step treatment.

    Is Karisma the same as Sculptra or polycaprolactone (PCL)?

    No. Sculptra uses poly-L-lactic acid (PLLA) and PCL devices use polycaprolactone — both are synthetic biostimulators that take 3+ months to build collagen. Karisma uses bioengineered human collagen that integrates immediately and shows visible result at 4 weeks. Karisma replenishes; PCL/PLLA stimulate.

    Is Karisma halal-friendly for Muslim patients?

    Yes. Karisma uses recombinant human collagen produced via E. coli bacterial expression — zero porcine, bovine, or animal-derived material. VERZO CLINIC offers female doctors on request, private rooms for hijab removal, and a prayer room 2 minutes walk at Gateway Ekkamai.

    How long does Karisma last?

    Visible improvement appears at 4 weeks and peaks at 8–12 weeks after a 3-session protocol. Effects last 9–12 months with annual maintenance recommended. Native collagen synthesis triggered during treatment continues after the injected collagen is metabolized.

    Are there side effects?

    Mild redness, pinpoint marks at injection sites, and tenderness for 1–3 days are normal. Because Karisma uses recombinant human collagen (not animal-derived), allergic reactions are extremely rare. VERZO CLINIC uses only authentic GeneCell-supplied product with traceable lot numbers.

    How do I book a Karisma consultation at VERZO CLINIC?

    Consultation can be arranged via LINE @verzo, WhatsApp +66-95-326-6644, or walk-in. Clinic is 100m from BTS Ekkamai Exit 1 at 988-990-992 Sukhumvit Road, Bangkok. Open daily 10:00-19:00.

    Is Karisma safe during pregnancy or breastfeeding?

    Karisma is not recommended during pregnancy or breastfeeding due to insufficient safety data in these populations. VERZO CLINIC follows international consensus and asks all patients to disclose pregnancy status during consultation. Treatment can resume after weaning. If you discover pregnancy after treatment, the risk is generally considered low but inform your obstetrician.

    What payment options are available at VERZO CLINIC for Karisma?

    VERZO CLINIC accepts cash, credit cards (Visa, Mastercard, JCB, AMEX), bank transfer, and major Thai e-wallets (PromptPay, TrueMoney). We also accept international cards for medical-tourism patients with no foreign transaction fees on our side. Payment is confirmed at consultation.

    How does VERZO CLINIC ensure Karisma authenticity?

    VERZO CLINIC sources Karisma only through authorized Thailand distributors with verifiable lot numbers and supply chain. Original packaging is shown to patients on request, and lot numbers are recorded in your medical chart for traceability. We do NOT use grey-market or parallel-import products. Authenticity is fundamental to safety in aesthetic medicine.

    What languages does VERZO CLINIC offer for Karisma consultations?

    VERZO CLINIC offers consultations in Thai (native), English (fluent), Japanese, Mandarin Chinese, Korean, Spanish, Portuguese, French, Bahasa Melayu, and basic Arabic. For international patients we recommend booking ahead via LINE @verzo or WhatsApp +66-95-326-6644 to ensure language-matched doctor availability. Translation support is available on request for less common languages.

    How often should I schedule Karisma maintenance treatments?

    For sustained results, Karisma maintenance is typically recommended every 6–12 months. Individual cadence varies by metabolism, lifestyle factors (sun exposure, smoking, exercise), and original treatment intensity. Your VERZO CLINIC doctor will create a personalized maintenance schedule during your follow-up review.

    Book Karisma at VERZO CLINIC Bangkok

    Address: VERZO CLINIC, 988-990-992 Sukhumvit Road, near BTS Ekkamai Exit 1 (100m walk), Bangkok 10110, Thailand.

    Hours: Open daily 10:00-19:00.

    Contact: LINE @verzo · WhatsApp +66-95-326-6644 · WeChat available

    Languages: Thai, English, Japanese, Chinese (Mandarin), basic Arabic and Bahasa Melayu.

    Halal-friendly: Recombinant collagen — zero animal-derived material. Private rooms for hijab removal, prayer room at Gateway Ekkamai 2 min walk, female doctor available on request.

    Rh-Collagen Skinbooster Program — VERZO CLINIC Bangkok aesthetic treatment

    Karisma

    Rh-Collagen Skinbooster Program

    Recombinant human type III collagen for skin structure, elasticity and fine lines — dosing planned by a doctor.

    Duration30–45 min
    Downtime1–2 days
    Pain Level
    3/10
    Mild
    Results Last6–12 Months

    What's in this price

    VAT
    None
    Doctor consultation
    None
    Doctor's fee
    None
    Numbing / anaesthetic
    None
    Follow-up visit
    None
    Aftercare products
    None

    Medical services at a licensed clinic are VAT-exempt under the Thai Revenue Code.

    This is a starting price. The actual plan is set by the doctor at your consultation.

    Skin Concerns

    ปัญหาผิวที่ Karisma แก้ไขได้

    ผิวหย่อนคล้อย

    คอลลาเจนลดลงตามวัย ผิวไม่กระชับ ขาดความยืดหยุ่น

    ริ้วรอยเล็กๆ

    เส้นริ้วรอยบริเวณใต้ตา หน้าผาก และร่องแก้ม

    ผิวหยาบกร้าน

    ผิวขาดความเนียนนุ่ม สัมผัสไม่เรียบ

    ผิวไม่ยืดหยุ่น

    ผิวเหี่ยว ขาดน้ำ กดแล้วไม่คืนตัว

    Recombinant Human Collagen

    Karisma — Rh Collagen Type III

    Karisma คือสารฉีดที่มีส่วนประกอบของ Recombinant Human Type III Collagen ผลิตจากเทคโนโลยีชีวภาพขั้นสูง ไม่ได้สกัดจากสัตว์ ทำให้มีโครงสร้างเหมือนคอลลาเจนในร่างกายมนุษย์ ช่วยฟื้นฟูโครงสร้างผิว เพิ่มความยืดหยุ่น และลดริ้วรอยเล็กๆ อย่างเป็นธรรมชาติ

    Bio-Identical

    โครงสร้างเหมือนคอลลาเจนในร่างกาย ลดความเสี่ยงแพ้

    Biotech Production

    ผลิตจากเทคโนโลยี Recombinant ไม่ได้สกัดจากสัตว์

    Structural Repair

    ฟื้นฟูโครงร่างคอลลาเจนในชั้นผิวหนังแท้ (Dermis)

    Karisma Rh Collagen Benefits

    Preparation & aftercare

    Your care plan for Karisma Program

    Research-informed guidance for this treatment type. Your doctor’s written plan after assessment always takes priority.

    Before your appointment

    • Tell the doctor about allergies, infection or inflammation, bleeding tendency, medicines and supplements, immune conditions, prior implants or filler, and pregnancy or breastfeeding.
    • Confirm the exact product and whether the treatment plan requires product-specific massage; do not assume all biostimulators have the same aftercare.

    After treatment

    • Keep the sites clean and avoid pressing or massage unless the written product-specific plan instructs it.
    • Use gentle skincare and ask when to resume makeup, exercise, heat exposure and active products.
    • Keep the product record and attend the planned review.

    What may be expected

    • Temporary bumps, swelling, redness, tenderness or bruising may occur; the expected timeline differs by formulation and injection depth.

    Contact us promptly

    • Contact the clinic for persistent nodules, increasing heat or redness, drainage, fever, or delayed inflammation.
    • Seek urgent care for unusual pain, marked skin-colour change, vision change or neurological symptoms.

    1:1 follow-up

    Before you leave, the team records your treatment, expected recovery, follow-up timing and direct contact path. A doctor reviews concerns when needed.

    Follow up on LINEFollow up on WhatsApp

    Evidence & patient information

    Patient Privacy

    Your Privacy is Our Priority

    We adhere to strict medical ethics and data protection laws (PDPA)

    Informed Consent

    Every procedure begins with a clear explanation and signed consent form. You will fully understand the treatment, risks, and aftercare before we proceed.

    Photo Privacy

    All before & after photos displayed on our site are used only with explicit written permission from our patients. We respect your right to anonymity.

    Data Security

    Your medical records are stored securely and remain confidential. We never share your data with third parties.

    Results vary depending on individual skin and body conditions

    Please consult a physician before treatment

    Results are not promised

    VERZO CLINIC — 988-990-992 Sukhumvit Road, Ekkamai, Bangkok 10110, Thailand. Open daily 10:00–19:00 (Bangkok time). Staff can assist in Thai, English, Japanese and Chinese.

    Contact: LINE @verzo · WhatsApp +66 95 326 6644