How much does Nucleofill cost in Bangkok 2026?

Nucleofill Strong 2cc at VERZO CLINIC Bangkok is ฿18,999 per box in 2026 — substantially less than Singapore (SGD 950–1,400) or Tokyo (¥75,000–120,000). A typical full-face protocol uses 1 box; large areas or combined neck/hands need 2.

What is the difference between Nucleofill and Rejuran?

Both are polynucleotide skin boosters but Rejuran is Korean (PN at lower concentration ~2%) while Nucleofill is Italian (Promoitalia, 2.5% PN concentration — among the highest available). Nucleofill comes in 4 variants (Medium, Strong, Soft Plus, Medium Plus) for customized intensity. Rejuran has 3 variants (Healer, I, S/HB).

How is Nucleofill different from HA fillers like Profhilo?

Profhilo uses hyaluronic acid for hydration and bio-remodelling. Nucleofill uses PDRN (polynucleotide) which works through a different mechanism — activating purinergic receptors on cell surfaces to trigger genuine tissue repair, collagen synthesis, and DNA-level cell regeneration. Many patients combine the two for layered effect.

How long does Nucleofill last?

Nucleofill effects build progressively over 1–3 months and last 9–12 months. Initial hydration appears in 1–2 hours, metabolic activation peaks at 48 hours, the polynucleotide degrades over 7–10 days, but the regenerative effects on collagen and tissue continue for many months after. Maintenance every 9–12 months is typical.

Is Nucleofill suitable for under-eye treatment?

Yes. Nucleofill Soft Plus or Medium Plus are designed for delicate under-eye skin — improving dark circles, hollow appearance, and skin texture. Unlike HA fillers under the eye (which can pool or create Tyndall effect), Nucleofill regenerates the skin itself rather than adding volume.

Are there side effects?

Mild redness and swelling for 1–2 days are normal. Nucleofill is well-tolerated as PDRN is structurally similar to human DNA. Rare side effects include bruising at injection sites. Not for patients with active infections or pregnant/breastfeeding women. VERZO CLINIC uses only authentic Promoitalia product with traceable lot numbers.

How do I book a Nucleofill consultation at VERZO CLINIC?

Free consultation is available via LINE @verzo, WhatsApp +66-95-326-6644, or walk-in. Clinic is 100m from BTS Ekkamai Exit 1 at 988-990-992 Sukhumvit Road, Bangkok. Open daily 10:00-19:00.

Is Nucleofill safe during pregnancy or breastfeeding?

Nucleofill is not recommended during pregnancy or breastfeeding due to insufficient safety data in these populations. VERZO CLINIC follows international consensus and asks all patients to disclose pregnancy status during consultation. Treatment can resume after weaning. If you discover pregnancy after treatment, the risk is generally considered low but inform your obstetrician.

Can I combine Nucleofill with other treatments in the same visit?

Yes — Nucleofill can be combined with most other VERZO CLINIC treatments. Common combinations include Nucleofill with Botox (for upper-face wrinkles), HIFU/Ultraformer (for skin tightening), or other skinbooster treatments for layered results. We typically space combination treatments 1–2 weeks apart, but same-day combinations are possible for compatible procedures. Your doctor will recommend the optimal sequence during your free consultation.

What payment options are available at VERZO CLINIC for Nucleofill?

VERZO CLINIC accepts cash, credit cards (Visa, Mastercard, JCB, AMEX), bank transfer, and major Thai e-wallets (PromptPay, TrueMoney). We also accept international cards for medical-tourism patients with no foreign transaction fees on our side. Multi-session packages and membership programs offer 10–20% savings vs single-session pricing. Contact LINE @verzo for current promotions.

How does VERZO CLINIC ensure Nucleofill authenticity?

VERZO CLINIC sources Nucleofill only through authorized Thailand distributors with verifiable lot numbers and supply chain. Original packaging is shown to patients on request, and lot numbers are recorded in your medical chart for traceability. We do NOT use grey-market or parallel-import products. Authenticity is fundamental to safety in aesthetic medicine.

What languages does VERZO CLINIC offer for Nucleofill consultations?

VERZO CLINIC offers consultations in Thai (native), English (fluent), Japanese, Mandarin Chinese, Korean, Spanish, Portuguese, French, Bahasa Melayu, and basic Arabic. For international patients we recommend booking ahead via LINE @verzo or WhatsApp +66-95-326-6644 to ensure language-matched doctor availability. Translation support is available on request for less common languages.

How often should I schedule Nucleofill maintenance treatments?

For sustained results, Nucleofill maintenance is typically recommended every 6–12 months. Individual cadence varies by metabolism, lifestyle factors (sun exposure, smoking, exercise), and original treatment intensity. Your VERZO CLINIC doctor will create a personalized maintenance schedule during your follow-up review. Members enjoy priority booking and package pricing on maintenance sessions.

Nucleofill Polynucleotide Gel Bangkok | VERZO CLINIC Ekkamai

Name: Nucleofill Polynucleotide Gel
Brand: Nucleofill
Price: 18999 THB
Availability: InStock
Rating: 4.8 (52 reviews)

Nucleofill by Promoitalia (Italy) is a premium 2.5% polynucleotide gel derived from wild salmon sperm DNA. It works through PDRN receptor activation — a lock-and-key mechanism where polynucleotide molecules activate purinergic receptors on cell surfaces, triggering deep tissue repair and collagen synthesis. Available in 4 variants (Medium, Strong, Soft Plus, Medium Plus) for customized treatment. Pharmacokinetics: hydration 1-2 hours, metabolic activation 48 hours, degradation 7-10 days. Pricing at VERZO CLINIC: from ฿18,999 per session. CE certified Italian manufacturing. Available at VERZO CLINIC Bangkok near BTS Ekkamai. Prices may vary. Consultation required for personalized treatment plan.

Expert Insight on Nucleofill

"Nucleofill's PDRN works through a lock-and-key mechanism — the polynucleotide molecules activate purinergic receptors on cell surfaces, triggering genuine tissue repair at the cellular level. This is fundamentally different from HA fillers which simply add water-binding volume. For patients with sun-damaged or aging skin needing real regeneration, Nucleofill is my first choice over hydration-only boosters." — Dr. Waleerat Thaweebanchongsin, Aesthetic Medicine Specialist, VERZO CLINIC

Nucleofill Key Facts — 2026

2.5% PDRN concentration — among the highest available for polynucleotide treatments
Manufacturer: Promoitalia (Italy) — premium European GMP
4 variants: Medium, Strong, Soft Plus, Medium Plus — customized to treatment area
Pharmacokinetics: hydration 1-2h → metabolic activation 48h → degradation 7-10 days → elimination 15 days
Derived from wild salmon sperm DNA — high biocompatibility with human cells
Results last 9-12 months with progressive improvement over 1-3 months
Nucleofill polynucleotide at VERZO CLINIC: from ฿18,999 per session (40-60% less than Singapore or Japan)

About Nucleofill Polynucleotide Gel

Manufacturer: Promoitalia (Italy). Certifications: CE (Europe), Italian GMP manufacturing.

How it works: Nucleofill contains PDRN (polydeoxyribonucleotide) derived from wild salmon sperm DNA. PDRN activates cell receptors through a "lock and key" mechanism — the polynucleotide molecules fit precisely into purinergic receptors on cell surfaces, triggering cellular repair, collagen synthesis, and tissue regeneration. Pharmacokinetics: hydration effect in 1-2 hours, metabolic activation at 48 hours, degradation at 7-10 days, complete elimination at 15 days.

Key technology: PDRN (polydeoxyribonucleotide) from wild salmon sperm at 2.5% concentration — activates purinergic cell receptors like a lock-and-key mechanism

Treatment Areas

Full face
Under-eye area
Neck
Hands
Body areas with skin laxity

Who Is Nucleofill Best For?

Deep wrinkles and sagging skin needing intensive repair
Those seeking long-lasting anti-aging results (9-12 months)
Under-eye dark circles and hollows
UV-damaged skin requiring deep regeneration
Patients preferring premium European products with clinical evidence
Skin that has lost elasticity and bounce

Nucleofill vs Other Polynucleotides

PDRN lock-and-key receptor activation — scientifically targeted cell repair
4 product variants (Medium, Strong, Soft Plus, Medium Plus) for customized treatment intensity
Pharmacokinetics timeline: hydration 1-2h → metabolic activation 48h → degradation 7-10 days → elimination 15 days
Premium Italian manufacturing by Promoitalia
2.5% PN concentration — among the highest available for deep tissue repair
Wild salmon sperm derived — high biocompatibility with human DNA

Aftercare for Nucleofill

Mild swelling and redness for 1-2 days is normal
Avoid heat exposure for 24-48 hours
Stay hydrated to support tissue regeneration
Results build progressively over 1-3 months
Consider maintenance session at 9-12 months

Nucleofill Pricing at VERZO CLINIC Bangkok

Nucleofill polynucleotide at VERZO CLINIC: from ฿18,999 per session. Prices may vary. Consultation required for personalized treatment plan.

Location: VERZO CLINIC, 988-990-992 Sukhumvit Road, near BTS Ekkamai, Bangkok. Open daily 10:00-19:00.

Contact: LINE @verzo | WhatsApp +66-95-326-6644