Nucleofill
Awaken New Skin from Within Program
PDRN 2.5% from wild salmon DNA by Promoitalia, Italy. Lock-and-key receptor activation for deep tissue repair. 4 variants (Medium, Strong, Soft Plus, Medium Plus).
What's in this price
- VAT
- None
- Doctor consultation
- None
- Doctor's fee
- None
- Numbing / anaesthetic
- None
- Follow-up visit
- None
- Aftercare products
- None
Medical services at a licensed clinic are VAT-exempt under the Thai Revenue Code.
This is a starting price. The actual plan is set by the doctor at your consultation.
Skin that's lost its bounce
Deep lines. Sagging. Loss of elasticity. These aren't just 'signs of aging.' They're signs your skin has stopped regenerating.
Nucleofill repairs at the deepest level. Italian PN gel technology. Comprehensive tissue regeneration.
How Nucleofill Works
PDRN from wild salmon sperm activates purinergic cell receptors through a lock-and-key mechanism — triggering deep tissue repair and collagen synthesis at the cellular level.
PDRN Lock & Key
Polynucleotide molecules fit precisely into purinergic receptors on cell surfaces, triggering cellular repair
Collagen Synthesis
Activated cells produce new collagen and elastin for structural skin renewal
Hydration (1-2 Hours)
Immediate deep hydration effect within 1-2 hours of treatment
Metabolic Activation (48h)
Full metabolic activation at 48 hours — fibroblasts begin tissue regeneration
Degradation (7-10 Days)
PN gel naturally degrades over 7-10 days, with complete elimination by day 15
4 Variant Options
Medium, Strong, Soft Plus, Medium Plus — customized intensity for face, neck, under-eye, and body
The Outcomes You'll Love
With Nucleofill, you can expect:
Deep hydration and improved skin elasticity
Skin restoration and collagen stimulation
Reduced wrinkles and deep lines
Smooth, radiant, and youthful skin
Natural lifting effect that lasts 9-12 months
Results Timeline
Track your transformation journey
Initial Healing
Skin feels more hydrated. Minor swelling subsides. Initial texture improvement.
Visible Changes
Collagen production begins. Wrinkles start to soften. Skin tone improves.
Peak Results
Peak repair phase. Deep tissue repair complete. Lifting effect apparent.
Long-lasting Benefits
Results continue. Skin maintains youthful appearance. Consider maintenance session.
Your Privacy is Our Priority
We adhere to strict medical ethics and data protection laws (PDPA)
Informed Consent
Every procedure begins with a clear explanation and signed consent form. You will fully understand the treatment, risks, and aftercare before we proceed.
Photo Privacy
All before & after photos displayed on our site are used only with explicit written permission from our patients. We respect your right to anonymity.
Data Security
Your medical records are stored securely and remain confidential. We never share your data with third parties.
Why Choose Nucleofill
Italian Quality
Premium European manufacturing standards
Thai FDA (อย.) Registered
European medical device certification
2.5% Concentration
Highest PN concentration for deep repair
licensed physicians
International standards at Verzo Clinic
Global Client Support
Thai, Chinese, English, Japanese speakers
Who Is It For?
You have deep wrinkles and sagging skin that need intensive repair
You're looking for long-lasting skin-renewal results (9-12 months)
You want under-eye treatment for dark circles and hollows
You prefer premium European products with proven results
Your Safety Is Our Priority
At Verzo Clinic, you receive medical-standard care and rigorous product verification.
Thai FDA (อย.) Registered
European medical device standards
Informed Consent
Full written consent and after-care plan
5 Authenticity Checks
Packaging, serial, expiry, certificate, kit
Bilingual Support
Interpreters and experienced physicians
Common questions
Muslim-Friendly Service
Your faith, respected. Your privacy, assured.
Product Safety & Origin
Privacy & Cultural Accommodations
Female-Only Team Available
Request an all-female medical team for your treatment
Private Suite Assured
Enclosed private rooms - safe to remove hijab
Prayer-Ready Suite
Qibla direction assistance available upon request
Muslim Staff On-Site
We are proud to have Muslim staff members on our team who provide innate cultural understanding and ensure your religious needs (modesty & halal concerns) are met with genuine care, without you having to explain.
Dedicated Prayer Rooms Nearby
Fully equipped prayer rooms (separate for men/women with built-in ablution/wudu area) are located at Gateway Ekkamai Mall (M Floor).
Directly connected via BTS Ekkamai skywalk (2 min walk from clinic)
Is this treatment suitable for Muslims?
Yes. This product is fully synthetic/marine-derived and contains no porcine or prohibited animal ingredients. Female medical team available upon request.
Related Treatments
Discover other treatments that complement Nucleofill
Ready for Youthful, Radiant Skin?
Book your and discover how Nucleofill can rejuvenate your skin from within.
Results may vary by individual. Consultation required to assess suitability.
Preparation & aftercare
Your care plan for Nucleofill Italian PN Treatment Program
Research-informed guidance for this treatment type. Your doctor’s written plan after assessment always takes priority.
Before your appointment
- Tell the doctor about allergies, infection or inflammation, bleeding tendency, medicines and supplements, immune conditions, prior implants or filler, and pregnancy or breastfeeding.
- Confirm the exact product and whether the treatment plan requires product-specific massage; do not assume all biostimulators have the same aftercare.
After treatment
- Keep the sites clean and avoid pressing or massage unless the written product-specific plan instructs it.
- Use gentle skincare and ask when to resume makeup, exercise, heat exposure and active products.
- Keep the product record and attend the planned review.
What may be expected
- Temporary bumps, swelling, redness, tenderness or bruising may occur; the expected timeline differs by formulation and injection depth.
Contact us promptly
- Contact the clinic for persistent nodules, increasing heat or redness, drainage, fever, or delayed inflammation.
- Seek urgent care for unusual pain, marked skin-colour change, vision change or neurological symptoms.
1:1 follow-up
Before you leave, the team records your treatment, expected recovery, follow-up timing and direct contact path. A doctor reviews concerns when needed.
Evidence & patient information
- U.S. Food and Drug Administration: Dermal Fillers (Soft Tissue Fillers)
- Dermatologic Surgery: Consensus Recommendations for Combined Aesthetic Interventions Using Calcium Hydroxylapatite
- Journal of Cosmetic Dermatology: Clinical Experience with Polycaprolactone-Based Dermal Filler Complications
- Journal of Cosmetic Dermatology: Consensus report on the use of PN-HPT in aesthetic medicine
Results vary depending on individual skin and body conditions
Please consult a physician before treatment
Results are not promised