แก้ร่องแก้ม: ฟิลเลอร์ vs เส้นไหม vs Sculptra — VERZO CLINIC กรุงเทพฯ
TL;DR: Nasolabial folds deepen due to a combination of factors: loss of cheek fat pad volume causing the cheek to descend, bone resorption in the midface, reduced collagen and elastin in the skin, and repeated muscle movement from smiling.
Written by Dr. Waleerat Thaweebanchongsin, licensed physician with over 10 years of aesthetic-medicine experience. VERZO CLINIC near BTS Ekkamai. Free consultations via LINE @verzo.
Last updated: April 2026
Nasolabial folds deepen due to a combination of factors: loss of cheek fat pad volume causing the cheek to descend, bone resorption in the midface, reduced collagen and elastin in the skin, and repeated muscle movement from smiling.
Filler is the most common treatment but not always appropriate on its own. For mild folds, filler in the fold itself works well. For moderate to deep folds, the appropriate approach is often restoring cheek volume above the fold to lift the tissue, combined with filler in the fold.
HA fillers like Juvederm Volift in the nasolabial folds typically last 9-15 months. The area has significant movement, which breaks down filler faster than static areas. Touch-ups every 9-12 months maintain results.
Thread lifts can help nasolabial folds by lifting the cheek tissue that is causing the fold to deepen. PDO or PLLA threads placed along the cheek provide lift and stimulate collagen. This approach works well for folds caused primarily by sagging.
Sculptra restores volume above the fold by stimulating collagen production in the midface. Over 2-3 sessions, it rebuilds the natural volume that age has taken away, reducing fold depth from above rather than filling the fold directly.
For deep folds, a combination approach yields good results: Sculptra for midface volume restoration, thread lift for mechanical cheek support, and a small amount of HA filler directly in the fold for immediate improvement. This three-level approach addresses all causes.
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