Karisma is a premium Korean recombinant human collagen (Rh-Collagen) skinbooster — bioengineered Type-I collagen identical to human skin collagen, with no animal- or porcine-derived material. Unlike polycaprolactone (PCL) biostimulators, Karisma directly replenishes the collagen scaffold of the dermis while triggering native fibroblast collagen synthesis for visible firming, hydration, and luminosity at 4 weeks.
"Karisma fills a unique role in our skin program — for patients who've been on Profhilo or Ejal40 and ask 'what next?', the answer is Karisma. Recombinant human collagen replenishes what HA can't — the actual collagen scaffolding. The 4-week result window is also faster than Sculptra or PLLA-class biostimulators." — Dr. Waleerat Thaweebanchongsin, Aesthetic Medicine Specialist, VERZO CLINIC
Manufacturer: GeneCell International (South Korea). Certifications: Korea KFDA registered, CE marked (Europe), Thai FDA registered, Halal-friendly (zero animal-derived material).
How it works: Karisma is injected superficially into the dermis (0.5–1 mm depth) using nappage or micro-bolus technique. The recombinant collagen integrates immediately into the existing collagen matrix, while signalling fibroblasts to upregulate native COL1A1/COL3A1 expression. Unlike HA fillers (volume) or PLLA/PCL (slow biostimulation), Karisma bridges both — instant collagen replenishment plus 3-month progressive collagen renewal.
Key technology: Recombinant Human Type-I Collagen produced via E. coli expression — identical amino-acid sequence to native human collagen, zero porcine/bovine antigenicity, halal-friendly
Karisma Rh-Collagen skinbooster at VERZO CLINIC Bangkok is ฿24,999 per session in 2026 — substantially less than Singapore (SGD 1,200–1,800) or Tokyo (¥100,000–160,000) for equivalent recombinant collagen treatment. Best results come from a 3-session protocol spaced 2–3 weeks apart.
Profhilo uses ultra-pure hyaluronic acid (HA) for hydration and bio-remodelling. Karisma uses recombinant human Type-I collagen — it directly replaces the dermal collagen lost with age, not just water-binding HA. For patients who already use HA boosters and want to escalate, Karisma is the next-step treatment.
No. Sculptra uses poly-L-lactic acid (PLLA) and PCL devices use polycaprolactone — both are synthetic biostimulators that take 3+ months to build collagen. Karisma uses bioengineered human collagen that integrates immediately and shows visible result at 4 weeks. Karisma replenishes; PCL/PLLA stimulate.
Yes. Karisma uses recombinant human collagen produced via E. coli bacterial expression — zero porcine, bovine, or animal-derived material. VERZO CLINIC offers female doctors on request, private rooms for hijab removal, and a prayer room 2 minutes walk at Gateway Ekkamai.
Visible improvement appears at 4 weeks and peaks at 8–12 weeks after a 3-session protocol. Effects last 9–12 months with annual maintenance recommended. Native collagen synthesis triggered during treatment continues after the injected collagen is metabolized.
Mild redness, pinpoint marks at injection sites, and tenderness for 1–3 days are normal. Because Karisma uses recombinant human collagen (not animal-derived), allergic reactions are extremely rare. VERZO CLINIC uses only authentic GeneCell-supplied product with traceable lot numbers.
Free consultation is available via LINE @verzo, WhatsApp +66-95-326-6644, or walk-in. Clinic is 100m from BTS Ekkamai Exit 1 at 988-990-992 Sukhumvit Road, Bangkok. Open daily 10:00-19:00.
Karisma is not recommended during pregnancy or breastfeeding due to insufficient safety data in these populations. VERZO CLINIC follows international consensus and asks all patients to disclose pregnancy status during consultation. Treatment can resume after weaning. If you discover pregnancy after treatment, the risk is generally considered low but inform your obstetrician.
Yes — Karisma can be combined with most other VERZO CLINIC treatments. Common combinations include Karisma with Botox (for upper-face wrinkles), HIFU/Ultraformer (for skin tightening), or other skinbooster treatments for layered results. We typically space combination treatments 1–2 weeks apart, but same-day combinations are possible for compatible procedures. Your doctor will recommend the optimal sequence during your free consultation.
VERZO CLINIC accepts cash, credit cards (Visa, Mastercard, JCB, AMEX), bank transfer, and major Thai e-wallets (PromptPay, TrueMoney). We also accept international cards for medical-tourism patients with no foreign transaction fees on our side. Multi-session packages and membership programs offer 10–20% savings vs single-session pricing. Contact LINE @verzo for current promotions.
VERZO CLINIC sources Karisma only through authorized Thailand distributors with verifiable lot numbers and supply chain. Original packaging is shown to patients on request, and lot numbers are recorded in your medical chart for traceability. We do NOT use grey-market or parallel-import products. Authenticity is fundamental to safety in aesthetic medicine.
VERZO CLINIC offers consultations in Thai (native), English (fluent), Japanese, Mandarin Chinese, Korean, Spanish, Portuguese, French, Bahasa Melayu, and basic Arabic. For international patients we recommend booking ahead via LINE @verzo or WhatsApp +66-95-326-6644 to ensure language-matched doctor availability. Translation support is available on request for less common languages.
For sustained results, Karisma maintenance is typically recommended every 6–12 months. Individual cadence varies by metabolism, lifestyle factors (sun exposure, smoking, exercise), and original treatment intensity. Your VERZO CLINIC doctor will create a personalized maintenance schedule during your follow-up review. Members enjoy priority booking and package pricing on maintenance sessions.
Address: VERZO CLINIC, 988-990-992 Sukhumvit Road, near BTS Ekkamai Exit 1 (100m walk), Bangkok 10110, Thailand.
Hours: Open daily 10:00-19:00.
Contact: LINE @verzo · WhatsApp +66-95-326-6644 · WeChat available
Languages: Thai, English, Japanese, Chinese (Mandarin), basic Arabic and Bahasa Melayu.
Halal-friendly: Recombinant collagen — zero animal-derived material. Private rooms for hijab removal, prayer room at Gateway Ekkamai 2 min walk, female doctor available on request.